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睡眠時無呼吸症候群における気道陰圧負荷時の気道形態変化から病態および治療法を探る
https://tsurumi-u.repo.nii.ac.jp/records/1176
https://tsurumi-u.repo.nii.ac.jp/records/1176fc97a08b-51b2-407a-83dc-0a361108e9f4
名前 / ファイル | ライセンス | アクション |
---|---|---|
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Item type | 報告書 / Research Paper(1) | |||||
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公開日 | 2022-04-20 | |||||
タイトル | ||||||
言語 | ja | |||||
タイトル | 睡眠時無呼吸症候群における気道陰圧負荷時の気道形態変化から病態および治療法を探る | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Influence of negative pressure on airway configuration | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
言語 | ja | |||||
主題Scheme | Other | |||||
主題 | 睡眠時無呼吸症候群 | |||||
キーワード | ||||||
言語 | ja | |||||
主題Scheme | Other | |||||
主題 | 非肥満型OSA | |||||
キーワード | ||||||
言語 | ja | |||||
主題Scheme | Other | |||||
主題 | 気道形態 | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_18ws | |||||
資源タイプ | research report | |||||
研究代表者 |
石川, 千恵子
× 石川, 千恵子 |
|||||
報告年度 | ||||||
日付 | 2016-03-31 | |||||
日付タイプ | Issued | |||||
研究課題番号 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 研究課題/領域番号 : 25463039 | |||||
言語 | ja | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | 研究成果の概要(和文):本研究の目的は,睡眠時無呼吸患者(OSA)の気道陰圧負荷時の気道形態を観察することにより,非肥満型OSAのメカニズムを解明しその治療に役立てることである.本研究の趣旨に同意の得られた健常ボランティア1名に対し平常時および陰圧条件下におけるCT撮影を行った.その結果,平常時の楕円形を呈していた気道軸断面は,陰圧負荷時,後側壁が変形し,三角形を呈した.後鼻棘から喉頭蓋先端までの高さにおける気道体積は,平常時と比較し,陰圧下では59%減少した.このことから,気道の脆弱部は後側壁に存在し,脂肪増加や陰圧の影響により変形しやすいことが示唆された. | |||||
言語 | ja | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | 研究成果の概要(英文):In this study, to discover the weakness region in the airway, the airway configuration change under the negative pressure loading was observed.Subject was 33 year-old, female, who had no OSA. She agreed with the purpose of this study, and signed. The mask and the syringe were connected, and the pressure gage was set on the syringe. The device was pushed to her face, and covered her nose and mouth. She received the direction of her maximal inspiration, and the negative pressure within the syringe was measured as Max.NP. The airway was scanned via a CBCT (GALILEOS, Sirona, USA, NY) with 15 seconds, under following conditions; normal breathing and under S_NP. The configuration and volume of the airway were evaluated via image analysis software.At the maximal inspiration, the negative pressure within the syringe was 7.8 kPa. S_NP was 5.0 kPa (65% Max.NP). The airway configuration at normal breathing was elliptical shape. On the other hand, the airway under S_NP presented triangle shape. | |||||
言語 | en | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | ・2015(平成27)年度 科学研究費補助金 基盤研究(C) 研究成果報告書 | |||||
言語 | ja | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | ・研究期間 (年度):2013-04-01 – 2016-03-31 | |||||
言語 | ja | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | ・研究分野:補綴学 | |||||
言語 | ja | |||||
関連サイト | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-25463039/ | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa |