{"created":"2023-05-15T08:56:03.035842+00:00","id":1304,"links":{},"metadata":{"_buckets":{"deposit":"a0b7a828-ec88-461c-a0bc-1b0553e6785e"},"_deposit":{"created_by":10,"id":"1304","owners":[10],"pid":{"revision_id":0,"type":"depid","value":"1304"},"status":"published"},"_oai":{"id":"oai:tsurumi-u.repo.nii.ac.jp:00001304","sets":["100:101:103:189"]},"author_link":["776"],"item_10007_date_8":{"attribute_name":"報告年度","attribute_value_mlt":[{"subitem_date_issued_datetime":"2012-03-31","subitem_date_issued_type":"Issued"}]},"item_10007_description_13":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"研究成果の概要（和文）：ウシ血清中では、ナノバクテリアモノクロナール抗体に反応するタンパク質はすべてハイドロオキシアパタイト強く結合し、一種類のみがハイドロオキシアパタイトに陽イオン結合し、残りのタンパク質はハイドロオキシアパタイトにアフィニティー結合していた。ハイドロオキシアパタイトに対して陽イオン結合しているタンパク質の単離精製に成功した。残りのタンパク質はゲル濾過クロマトグラフィーにより分離を試みたがその電気泳動像は必ずしも分子量に従って分離されなかった。","subitem_description_language":"ja","subitem_description_type":"Abstract"},{"subitem_description":"研究成果の概要（英文）：We tried to purify the proteins that react to the monoclonal antibody for the Nano bacteria from the bovine serum. These proteins strongly bind to the hydroxyapatite. Among these proteins, one of them binds to hydroxyapatite by cationic reactions and others are bind to hydroxyapatite by affinity reactions for the calcium. We success in the purification of the protein that bind to hydroxyapatite by cationic reactions. By the gel filtration chromatography, other proteins that bind to the hydroxyapatite by affinity reactions for the calcium were collected in fixed fractions, however, we could not single out these proteins. By the mass analysis, these proteins included the components of the common fatty acid complexes that related to the life style diseases.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10007_description_14":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"・2011(平成23)年度 科学研究費補助金 基盤研究(C) 研究成果報告書","subitem_description_language":"ja","subitem_description_type":"Other"},{"subitem_description":"・研究期間 (年度)：2009 – 2011","subitem_description_language":"ja","subitem_description_type":"Other"},{"subitem_description":"・研究分野：医歯薬学","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_10007_description_9":{"attribute_name":"研究課題番号","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号 : 21592670","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_10007_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-21592670/","subitem_relation_type_select":"URI"}}]},"item_10007_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-05-18"}],"displaytype":"detail","filename":"21592670.pdf","filesize":[{"value":"229.6 kB"}],"format":"application/pdf","licensetype":"license_6","mimetype":"application/pdf","url":{"label":"21592670","url":"https://tsurumi-u.repo.nii.ac.jp/record/1304/files/21592670.pdf"},"version_id":"44f51953-67fa-41a5-8a3f-427e3d09863d"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"石灰化","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"ナノ粒子","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"歯学","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"社会医学","subitem_subject_language":"ja","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_researcher":{"attribute_name":"研究代表者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"NOMURA, Yoshiaki","creatorNameLang":"en"},{"creatorName":"野村, 義明","creatorNameLang":"ja"},{"creatorName":"ノムラ, ヨシアキ","creatorNameLang":"ja-Kana"}],"familyNames":[{"familyName":"NOMURA","familyNameLang":"en"},{"familyName":"野村","familyNameLang":"ja"},{"familyName":"ノムラ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Yoshiaki","givenNameLang":"en"},{"givenName":"義明","givenNameLang":"ja"},{"givenName":"ヨシアキ","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"776","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"90350587","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=90350587"},{"nameIdentifier":"776","nameIdentifierScheme":"WEKO著者ID"}]}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"人工的石灰化ナノ粒子合成と歯石沈着モデルの確立","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"人工的石灰化ナノ粒子合成と歯石沈着モデルの確立","subitem_title_language":"ja"},{"subitem_title":"Establishment of artificial synthesis of Nano bacteria and dental calculus","subitem_title_language":"en"}]},"item_type_id":"10007","owner":"10","path":["189"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2022-05-18"},"publish_date":"2022-05-18","publish_status":"0","recid":"1304","relation_version_is_last":true,"title":["人工的石灰化ナノ粒子合成と歯石沈着モデルの確立"],"weko_creator_id":"10","weko_shared_id":-1},"updated":"2024-08-01T08:48:23.949879+00:00"}