{"created":"2023-05-15T08:55:58.649985+00:00","id":1222,"links":{},"metadata":{"_buckets":{"deposit":"755d64e4-175e-45dc-bee9-0ad210c76189"},"_deposit":{"created_by":10,"id":"1222","owners":[10],"pid":{"revision_id":0,"type":"depid","value":"1222"},"status":"published"},"_oai":{"id":"oai:tsurumi-u.repo.nii.ac.jp:00001222","sets":["100:101:103:181"]},"author_link":["865"],"item_10007_date_8":{"attribute_name":"報告年度","attribute_value_mlt":[{"subitem_date_issued_datetime":"2015-03-31","subitem_date_issued_type":"Issued"}]},"item_10007_description_13":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"研究成果の概要（和文）：バイオフィルム初期形成は口腔内の歯および修復物表面へのペリクルタンパク質が吸着することから始まると考えられている。本研究では水晶発振子マイクロバランス法(QCM)を用いて、バイオフィルム抑制材料の基礎研究を行った。ペリクルタンパク質であるラクトフェリン、リゾチウム、ディフェンシンおよびムチンが金、シリカおよびチタンへの吸着特性の解析を行った。その結果、それぞれの材料の種類とペリクル成分の種類により、吸着特性が違い、特にSS結合の影響が大きく関与していることが明らかとなった。","subitem_description_language":"ja","subitem_description_type":"Abstract"},{"subitem_description":"研究成果の概要（英文）：The aim of the present study was to evaluate the adsorption behaviors of saliva pellicle proteins onto a gold, silica and titanium by using the quartz crystal microbalance method. As pellicle proteins, lactoferrin, lysozyme, defensin and mucin were evaluated. Adsorption amount of lactoferrin to silica was significantly lower than gold and titanium. Significant differences were detected between titanium and silica for the adsorption amounts of lysozyme. Chemical bond formation of sulfur atom of lysozyme and gold could be suggested. There were no significant differences of the adsorption amount of β-defensin among each substrate. For mucin adsorption, gold showed the highest adsorption amount. It is presumed that electrostatic repulsion caused less adsorption amounts of mucin to titanium and silica. In conclusion, the differences of the adsorption behaviors of pellicle proteins could be clearly identified.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10007_description_14":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"・2014(平成26)年度 科学研究費補助金 若手研究(B) 研究成果報告書","subitem_description_language":"ja","subitem_description_type":"Other"},{"subitem_description":"・研究期間 (年度)：2013-04-01 – 2015-03-31","subitem_description_language":"ja","subitem_description_type":"Other"},{"subitem_description":"・研究分野：歯科理工学","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_10007_description_9":{"attribute_name":"研究課題番号","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号 : 25861902","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_10007_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-25861902/","subitem_relation_type_select":"URI"}}]},"item_10007_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-04-29"}],"displaytype":"detail","filename":"25861902.pdf","filesize":[{"value":"447.5 kB"}],"format":"application/pdf","licensetype":"license_6","mimetype":"application/pdf","url":{"label":"25861902","url":"https://tsurumi-u.repo.nii.ac.jp/record/1222/files/25861902.pdf"},"version_id":"2a46d495-4fb9-4c8e-a554-f3325eabc57a"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"QCM","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"AFM","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"吸着","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"バイオフィルム","subitem_subject_language":"ja","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_researcher":{"attribute_name":"研究代表者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"YOSHIDA, Eiji","creatorNameLang":"en"},{"creatorName":"吉田, 英史","creatorNameLang":"ja"},{"creatorName":"ヨシダ, エイジ","creatorNameLang":"ja-Kana"}],"familyNames":[{"familyName":"YOSHIDA","familyNameLang":"en"},{"familyName":"吉田","familyNameLang":"ja"},{"familyName":"ヨシダ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Eiji","givenNameLang":"en"},{"givenName":"英史","givenNameLang":"ja"},{"givenName":"エイジ","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"865","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"30410054","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=30410054"},{"nameIdentifier":"865","nameIdentifierScheme":"WEKO著者ID"}]}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"感染制御材料の開発を目指したペリクルタンパク質吸着特性のQCMナノ解析","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"感染制御材料の開発を目指したペリクルタンパク質吸着特性のQCMナノ解析","subitem_title_language":"ja"},{"subitem_title":"QCM nano analysis of the adsorption behavior of pellicle protein for the development of infection control material","subitem_title_language":"en"}]},"item_type_id":"10007","owner":"10","path":["181"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2022-04-29"},"publish_date":"2022-04-29","publish_status":"0","recid":"1222","relation_version_is_last":true,"title":["感染制御材料の開発を目指したペリクルタンパク質吸着特性のQCMナノ解析"],"weko_creator_id":"10","weko_shared_id":-1},"updated":"2024-08-02T02:05:21.890465+00:00"}