{"created":"2023-05-15T08:55:58.399346+00:00","id":1218,"links":{},"metadata":{"_buckets":{"deposit":"2a74e2c4-1ee7-49ed-ad9b-dd97f093edef"},"_deposit":{"created_by":10,"id":"1218","owners":[10],"pid":{"revision_id":0,"type":"depid","value":"1218"},"status":"published"},"_oai":{"id":"oai:tsurumi-u.repo.nii.ac.jp:00001218","sets":["100:101:103:181"]},"author_link":["795"],"item_10007_date_8":{"attribute_name":"報告年度","attribute_value_mlt":[{"subitem_date_issued_datetime":"2015-03-31","subitem_date_issued_type":"Issued"}]},"item_10007_description_13":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"研究成果の概要（和文）：本研究では、マウス皮膚線維芽細胞にストレスを負荷し、幹細胞を分離できるか検討した。7週齢マウスを用いてストレス抵抗性細胞の分離し、核型を検討したところ、染色体数に異常は認められなかった。また分離した細胞は幹細胞マーカーであるSSEA1に陽性であった。以上の結果よりマウス皮膚線維芽細胞に化学的ストレス負荷を行い、SSEA1陽性細胞の分離を行うことが出来たことより、幹細胞がストレスに抵抗性を持ち、その性質を用いて分離できる可能性が示唆された。","subitem_description_language":"ja","subitem_description_type":"Abstract"},{"subitem_description":"研究成果の概要（英文）：In this study, we examined to conduct trypsin treatment to dermal fibroblasts and isolate stem cells. We isolated stress tolerant cells from 7-week-old mice fibroblasts. The cells did not show abnormal karyotypes and are positive for SSEA-1. These results suggested that stem cells are stress-tolerant and we could isolate from mice fibroblasts.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10007_description_14":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"・2014(平成26)年度 科学研究費補助金 若手研究(B) 研究成果報告書","subitem_description_language":"ja","subitem_description_type":"Other"},{"subitem_description":"・研究期間 (年度)：2012-04-01 – 2015-03-31","subitem_description_language":"ja","subitem_description_type":"Other"},{"subitem_description":"・研究分野：歯科矯正学","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_10007_description_9":{"attribute_name":"研究課題番号","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号 : 24792317","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_10007_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-24792317/","subitem_relation_type_select":"URI"}}]},"item_10007_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-04-29"}],"displaytype":"detail","filename":"24792317.pdf","filesize":[{"value":"313.2 kB"}],"format":"application/pdf","licensetype":"license_6","mimetype":"application/pdf","url":{"label":"24792317","url":"https://tsurumi-u.repo.nii.ac.jp/record/1218/files/24792317.pdf"},"version_id":"cce114d0-bdd5-4a5d-a737-9aabada0d431"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"幹細胞","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"ストレス","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"核型","subitem_subject_language":"ja","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_researcher":{"attribute_name":"研究代表者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"WADA, Satoshi","creatorNameLang":"en"},{"creatorName":"和田, 悟史","creatorNameLang":"ja"},{"creatorName":"ワダ, サトシ","creatorNameLang":"ja-Kana"}],"familyNames":[{"familyName":"WADA","familyNameLang":"en"},{"familyName":"和田","familyNameLang":"ja"},{"familyName":"ワダ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Satoshi","givenNameLang":"en"},{"givenName":"悟史","givenNameLang":"ja"},{"givenName":"サトシ","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"795","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"20581119","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=20581119"},{"nameIdentifier":"795","nameIdentifierScheme":"WEKO著者ID"}]}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"歯周組織に存在するストレス抵抗性多能性幹細胞の同定と歯周組織再生への応用","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"歯周組織に存在するストレス抵抗性多能性幹細胞の同定と歯周組織再生への応用","subitem_title_language":"ja"},{"subitem_title":"The isolation of stress-enduring stem cells in periodontal tissue and the application of periodontal guided tissue regeneration.","subitem_title_language":"en"}]},"item_type_id":"10007","owner":"10","path":["181"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2022-04-29"},"publish_date":"2022-04-29","publish_status":"0","recid":"1218","relation_version_is_last":true,"title":["歯周組織に存在するストレス抵抗性多能性幹細胞の同定と歯周組織再生への応用"],"weko_creator_id":"10","weko_shared_id":-1},"updated":"2024-08-01T23:17:07.884415+00:00"}