{"created":"2023-05-15T08:55:58.032606+00:00","id":1211,"links":{},"metadata":{"_buckets":{"deposit":"ffefc595-c2ee-41fd-a916-f8000e2bc002"},"_deposit":{"created_by":10,"id":"1211","owners":[10],"pid":{"revision_id":0,"type":"depid","value":"1211"},"status":"published"},"_oai":{"id":"oai:tsurumi-u.repo.nii.ac.jp:00001211","sets":["100:101:103:181"]},"author_link":["753"],"item_10007_date_8":{"attribute_name":"報告年度","attribute_value_mlt":[{"subitem_date_issued_datetime":"2015-03-31","subitem_date_issued_type":"Issued"}]},"item_10007_description_13":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"研究成果の概要（和文）：急性ストレスである歯科治療ストレスを想定したストレスモデルによって，ストレッサーが生体にストレスを生じる脳内過程と，その脳内過程に対する精神鎮静法薬や急性ストレスを軽減する可能性のある薬物の作用について検討を行った．その結果，急性ストレスによる脳内神経活動の変化と，その神経活動の変化に対する精神鎮静法薬，さらにストレス軽減作用を持つと考えられる新たな薬物の作用を明らかとした．","subitem_description_language":"ja","subitem_description_type":"Abstract"},{"subitem_description":"研究成果の概要（英文）：We studied effects of the acute stress on neural activity in the rat brain. The actions of the anxiolytis and sedatives on the central nervous system have been studied by microdialysis. This approach has shown that anxiolytis and sedatives suppress the accentuation of the locus coeruleus - medial prefrontal cortex neural activity, the accentuation of the ventral tegmental area - nucleus accumbens neuron activity, and the accentuation of the raphe - amygdala neuron activity in the stress state.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10007_description_14":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"・2014(平成26)年度 科学研究費補助金 基盤研究(C) 研究成果報告書","subitem_description_language":"ja","subitem_description_type":"Other"},{"subitem_description":"・研究期間 (年度)：2012-04-01 – 2015-03-31","subitem_description_language":"ja","subitem_description_type":"Other"},{"subitem_description":"・研究分野：歯科麻酔学","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_10007_description_9":{"attribute_name":"研究課題番号","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号 : 24593068","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_10007_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-24593068/","subitem_relation_type_select":"URI"}}]},"item_10007_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-04-29"}],"displaytype":"detail","filename":"24593068.pdf","filesize":[{"value":"89.3 kB"}],"format":"application/pdf","licensetype":"license_6","mimetype":"application/pdf","url":{"label":"24593068","url":"https://tsurumi-u.repo.nii.ac.jp/record/1211/files/24593068.pdf"},"version_id":"fc5eb915-591e-495c-aed8-5a444ec2c155"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"ストレス","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"神経科学","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"脳・神経","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"薬理学","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"歯学","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"精神鎮静法","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"抗不安薬","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"マイクロダイアリシス","subitem_subject_language":"ja","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_researcher":{"attribute_name":"研究代表者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"KAWAHARA, Hiroshi","creatorNameLang":"en"},{"creatorName":"河原, 博","creatorNameLang":"ja"},{"creatorName":"カワハラ, ヒロシ","creatorNameLang":"ja-Kana"}],"familyNames":[{"familyName":"KAWAHARA","familyNameLang":"en"},{"familyName":"河原","familyNameLang":"ja"},{"familyName":"カワハラ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Hiroshi","givenNameLang":"en"},{"givenName":"博","givenNameLang":"ja"},{"givenName":"ヒロシ","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"753","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"10186124","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=10186124"},{"nameIdentifier":"753","nameIdentifierScheme":"WEKO著者ID"}]}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"脳ニューラルネットワーク機構からの新しい歯科治療ストレス軽減法の開発","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"脳ニューラルネットワーク機構からの新しい歯科治療ストレス軽減法の開発","subitem_title_language":"ja"},{"subitem_title":"Development of new dental treatment stress reduction method from the brain neural network mechanism","subitem_title_language":"en"}]},"item_type_id":"10007","owner":"10","path":["181"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2022-04-29"},"publish_date":"2022-04-29","publish_status":"0","recid":"1211","relation_version_is_last":true,"title":["脳ニューラルネットワーク機構からの新しい歯科治療ストレス軽減法の開発"],"weko_creator_id":"10","weko_shared_id":-1},"updated":"2024-08-01T07:57:03.744894+00:00"}