{"created":"2023-05-15T08:55:57.144271+00:00","id":1194,"links":{},"metadata":{"_buckets":{"deposit":"f493951f-8b05-4de6-a2de-c4034fcfe513"},"_deposit":{"created_by":10,"id":"1194","owners":[10],"pid":{"revision_id":0,"type":"depid","value":"1194"},"status":"published"},"_oai":{"id":"oai:tsurumi-u.repo.nii.ac.jp:00001194","sets":["100:101:103:178"]},"author_link":["892"],"item_10007_date_8":{"attribute_name":"報告年度","attribute_value_mlt":[{"subitem_date_issued_datetime":"2016-03-31","subitem_date_issued_type":"Issued"}]},"item_10007_description_13":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"研究成果の概要（和文）：エンドセリンの口腔顔面領域における疼痛への関与について検討した．馴化を行い，7週齢のラット鼻毛部にエンドセリン-1を投与することによって，コントロール（生理食塩水）と比較して疼痛関連行動時間が増加し，エンドセリンの疼痛への関与が示唆された．またペントバルビタール麻酔下（50 mg/kg,i.p.）でラットの下顎骨を骨切削用歯科用エンジンを用いて切削し，下歯槽神経を露出させ，これを切断もしくは4－0絹糸で緩く結紮する手術を施行し，神経障害性疼痛モデルラット（切断・結紮）を作製した．","subitem_description_language":"ja","subitem_description_type":"Abstract"},{"subitem_description":"研究成果の概要（英文）：We investigated the effect of endothelin in orofacial pain. In the present study, the injection of endothelin-1(ET-1) at whisker pad prolonged the duration of the pain-related behavior. This result suggests that endothelin has some sort of effect for orofacial pain. Subsequently, we prepared the neuropathic pain model rat(transection・ligation).","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10007_description_14":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"・2015(平成27)年度 科学研究費補助金 若手研究(B) 研究成果報告書","subitem_description_language":"ja","subitem_description_type":"Other"},{"subitem_description":"・研究期間 (年度)：2014-04-01 – 2016-03-31","subitem_description_language":"ja","subitem_description_type":"Other"},{"subitem_description":"・研究分野：神経障害性疼痛","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_10007_description_9":{"attribute_name":"研究課題番号","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号 : 26861756","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_10007_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-26861756/","subitem_relation_type_select":"URI"}}]},"item_10007_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-04-20"}],"displaytype":"detail","filename":"26861756.pdf","filesize":[{"value":"162.0 kB"}],"format":"application/pdf","licensetype":"license_6","mimetype":"application/pdf","url":{"label":"26861756","url":"https://tsurumi-u.repo.nii.ac.jp/record/1194/files/26861756.pdf"},"version_id":"2cf0919b-243d-4f64-b123-97ef1783bc02"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"口腔顔面痛","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"エンドセリン","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"神経障害性疼痛","subitem_subject_language":"ja","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_researcher":{"attribute_name":"研究代表者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"YAMAMOTO, Toru","creatorNameLang":"en"},{"creatorName":"山本, 徹","creatorNameLang":"ja"},{"creatorName":"ヤマモト, トオル","creatorNameLang":"ja-Kana"}],"familyNames":[{"familyName":"YAMAMOTO","familyNameLang":"en"},{"familyName":"山本","familyNameLang":"ja"},{"familyName":"ヤマモト","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Toru","givenNameLang":"en"},{"givenName":"徹","givenNameLang":"ja"},{"givenName":"トオル","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"892","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"20707335","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=20707335"},{"nameIdentifier":"892","nameIdentifierScheme":"WEKO著者ID"}]}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"口腔顎顔面領域難治性慢性疼痛の発症機序解明と新たな治療展開","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"口腔顎顔面領域難治性慢性疼痛の発症機序解明と新たな治療展開","subitem_title_language":"ja"},{"subitem_title":"Explication of the mechanism and new therapy in refractory chronic orofacial pain","subitem_title_language":"en"}]},"item_type_id":"10007","owner":"10","path":["178"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2022-04-20"},"publish_date":"2022-04-20","publish_status":"0","recid":"1194","relation_version_is_last":true,"title":["口腔顎顔面領域難治性慢性疼痛の発症機序解明と新たな治療展開"],"weko_creator_id":"10","weko_shared_id":-1},"updated":"2024-08-02T03:12:27.237303+00:00"}