{"created":"2023-05-15T08:55:56.735942+00:00","id":1185,"links":{},"metadata":{"_buckets":{"deposit":"205a6481-0c33-4668-aba5-6c26d92d20fa"},"_deposit":{"created_by":10,"id":"1185","owners":[10],"pid":{"revision_id":0,"type":"depid","value":"1185"},"status":"published"},"_oai":{"id":"oai:tsurumi-u.repo.nii.ac.jp:00001185","sets":["100:101:103:178"]},"author_link":["887"],"item_10007_date_8":{"attribute_name":"報告年度","attribute_value_mlt":[{"subitem_date_issued_datetime":"2016-03-31","subitem_date_issued_type":"Issued"}]},"item_10007_description_13":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"研究成果の概要（和文）：う蝕細菌ミュータンスレンサ球菌のヒト口腔定着因子について、ヒトを含む動物間比較によって解析した。人工口腔装置による検討で、チンパンジー由来S. troglodytaeとS. dentirousettiはスクロース存在下でヒト由来S. mutans、S. sobrinus同様、エナメル歯片上にバイオフィルムを形成し、バイオフィルム直下のpHを低下させ、エナメル歯片を脱灰した。両菌のグルカン合成酵素(GTF)遺伝子の系統解析の結果、S. troglodytaeとS. dentirousettiは、それぞれS. mutans、S. sobrinusと類似した定着因子のGTFを有することがわかった。","subitem_description_language":"ja","subitem_description_type":"Abstract"},{"subitem_description":"研究成果の概要（英文）：Adherence factors of cariogenic bacteria, mutans streptococci, to human oral cavity were investigated by comparison among animals including humans. Streptococcus troglodytae and Streptococcus dentirousetti derived from chimpanzee formed biofilm on enamel slabs, decreased pH values underneath the biofilm and demineralized enamel like S. mutans and S. sobrinus from humans suggesting that both strains might be cariogenic. Phylogenetic analysis of glucosyltransferase (GTF) genes of S. troglodytae and S. dentirousetti showed that both strains possessed GTF genes as adherence factors similar to S. mutans and S. sobrinus, respectively.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10007_description_14":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"・2015(平成27)年度 科学研究費補助金 基盤研究(C) 研究成果報告書","subitem_description_language":"ja","subitem_description_type":"Other"},{"subitem_description":"・研究期間 (年度)：2013-04-01 – 2016-03-31","subitem_description_language":"ja","subitem_description_type":"Other"},{"subitem_description":"・研究分野：口腔細菌学、口腔生化学","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_10007_description_9":{"attribute_name":"研究課題番号","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号 : 25463270","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_10007_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-25463270/","subitem_relation_type_select":"URI"}}]},"item_10007_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-04-20"}],"displaytype":"detail","filename":"25463270.pdf","filesize":[{"value":"792.9 kB"}],"format":"application/pdf","licensetype":"license_6","mimetype":"application/pdf","url":{"label":"25463270","url":"https://tsurumi-u.repo.nii.ac.jp/record/1185/files/25463270.pdf"},"version_id":"0c547ca1-0258-4883-8cb2-a0f8af344d45"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"ミュータンスレンサ球菌","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"バイオフィルム","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"S. mutans","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"S. sobrinus","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"S. troglodyte","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"S. dentirousetti","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"う蝕","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"グルコシルトランスフェラーゼ","subitem_subject_language":"ja","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_researcher":{"attribute_name":"研究代表者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"IMAI, Susumu","creatorNameLang":"en"},{"creatorName":"今井, 奨","creatorNameLang":"ja"},{"creatorName":"イマイ, ススム","creatorNameLang":"ja-Kana"}],"familyNames":[{"familyName":"IMAI","familyNameLang":"en"},{"familyName":"今井","familyNameLang":"ja"},{"familyName":"イマイ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Susumu","givenNameLang":"en"},{"givenName":"奨","givenNameLang":"ja"},{"givenName":"ススム","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"887","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"80072958","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=80072958"},{"nameIdentifier":"887","nameIdentifierScheme":"WEKO著者ID"}]}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"動物種比較によるミュータンスレンサ球菌のヒト口腔定着因子の解明","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"動物種比較によるミュータンスレンサ球菌のヒト口腔定着因子の解明","subitem_title_language":"ja"},{"subitem_title":"Studies on the adherence factors of mutans streptococci to human oral cavity by comparative investigation among primates","subitem_title_language":"en"}]},"item_type_id":"10007","owner":"10","path":["178"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2022-04-20"},"publish_date":"2022-04-20","publish_status":"0","recid":"1185","relation_version_is_last":true,"title":["動物種比較によるミュータンスレンサ球菌のヒト口腔定着因子の解明"],"weko_creator_id":"10","weko_shared_id":-1},"updated":"2024-08-02T03:04:59.544929+00:00"}