{"created":"2023-05-15T08:55:55.676775+00:00","id":1166,"links":{},"metadata":{"_buckets":{"deposit":"7967e110-2e00-45f6-8729-54ae4920ac31"},"_deposit":{"created_by":10,"id":"1166","owners":[10],"pid":{"revision_id":0,"type":"depid","value":"1166"},"status":"published"},"_oai":{"id":"oai:tsurumi-u.repo.nii.ac.jp:00001166","sets":["100:101:103:177"]},"author_link":["873"],"item_10007_date_8":{"attribute_name":"報告年度","attribute_value_mlt":[{"subitem_date_issued_datetime":"2017-03-31","subitem_date_issued_type":"Issued"}]},"item_10007_description_13":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"研究成果の概要（和文）：チンパンジー口腔にはミュータンスレンサ球菌群のS. troglotytaeおよびS. dentirousettiが存在し、さらにミチスグループの新菌種をS. panodentisと命名した。研究代表者はS. troglotytae TKU31株の全遺伝子を解析し、S. mutansと類似の病原遺伝子を持つ事を明らかにした。ピロシーケンス法ではチンパンジー口腔細菌叢はヒトと類似のコアマイクロバイオームを持つことが明らかとなった。チンパンジーの口腔診査の結果では、う蝕が少なく、歯垢の蓄積が顕著であることを考慮すると、人類のう蝕起源は砂糖摂取が重要な因子である可能性が改めて示唆された。","subitem_description_language":"ja","subitem_description_type":"Abstract"},{"subitem_description":"研究成果の概要（英文）：We collected the dental plaque by the sterilized tooth brush, and analyzed them by the culture and metagenomic methods. As the results, we found two similar bacteria (Streptococcus troglotytae and S. dentirousetti) to S. mutans and S. sobrinus as the group of mutans streptococci. Moreover, we found a new species of the group of mitis streptococci, and named as S. panodentis. We analyzed whole genome sequence of the S. troglotytae TKU31, and these pathogenic genes were similar to those of S. mutans. We found the core microbiome of the oral flora in chimpanzees was similar to that in humans. Momoi et al., described that the dental caries was few, but huge accumulation of the dental plaque in the oral cavity of chimpanzees. Consequently, we confirmed an important factor for the human dental caries progression could be the consumption of the sugar, as previously described. We also supposed to be the oral microbiota coevolve with their host.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10007_description_14":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"・2016(平成28)年度 科学研究費補助金 若手研究(B) 研究成果報告書","subitem_description_language":"ja","subitem_description_type":"Other"},{"subitem_description":"・研究期間 (年度)：2014-04-01 – 2017-03-31","subitem_description_language":"ja","subitem_description_type":"Other"},{"subitem_description":"・研究分野：予防歯科学","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_10007_description_9":{"attribute_name":"研究課題番号","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号 : 26861847","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_10007_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-26861847/","subitem_relation_type_select":"URI"}}]},"item_10007_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-04-19"}],"displaytype":"detail","filename":"26861847.pdf","filesize":[{"value":"237.4 kB"}],"format":"application/pdf","licensetype":"license_6","mimetype":"application/pdf","url":{"label":"26861847","url":"https://tsurumi-u.repo.nii.ac.jp/record/1166/files/26861847.pdf"},"version_id":"31cc2b6d-ba6c-44f3-9f69-7b4e92e9338d"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"人類進化モデル","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"チンパンジー","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"口腔微生物叢","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"ピロシーケンス法","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"ホールゲノムシークエンス","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"ミュータンスレンサ球菌","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"う蝕","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"歯周疾患","subitem_subject_language":"ja","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_researcher":{"attribute_name":"研究代表者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"MIYANOHARA, Mayu","creatorNameLang":"en"},{"creatorName":"宮之原, 真由","creatorNameLang":"ja"},{"creatorName":"ミヤノハラ, マユ","creatorNameLang":"ja-Kana"}],"familyNames":[{"familyName":"MIYANOHARA","familyNameLang":"en"},{"familyName":"宮之原","familyNameLang":"ja"},{"familyName":"ミヤノハラ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Mayu","givenNameLang":"en"},{"givenName":"真由","givenNameLang":"ja"},{"givenName":"マユ","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"873","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"70460186","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=70460186"},{"nameIdentifier":"873","nameIdentifierScheme":"WEKO著者ID"}]}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"人類進化モデルを用いた口腔細菌叢の網羅的解析","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"人類進化モデルを用いた口腔細菌叢の網羅的解析","subitem_title_language":"ja"},{"subitem_title":"Comprehensive analysis of oral bacterial flora using human evolution model","subitem_title_language":"en"}]},"item_type_id":"10007","owner":"10","path":["177"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2022-04-19"},"publish_date":"2022-04-19","publish_status":"0","recid":"1166","relation_version_is_last":true,"title":["人類進化モデルを用いた口腔細菌叢の網羅的解析"],"weko_creator_id":"10","weko_shared_id":-1},"updated":"2024-08-02T02:29:14.132154+00:00"}