{"created":"2023-05-15T08:55:54.357038+00:00","id":1140,"links":{},"metadata":{"_buckets":{"deposit":"f1bbea98-f98b-492f-ab2e-3d67e5531143"},"_deposit":{"created_by":10,"id":"1140","owners":[10],"pid":{"revision_id":0,"type":"depid","value":"1140"},"status":"published"},"_oai":{"id":"oai:tsurumi-u.repo.nii.ac.jp:00001140","sets":["100:101:103:177"]},"author_link":["851"],"item_10007_date_8":{"attribute_name":"報告年度","attribute_value_mlt":[{"subitem_date_issued_datetime":"2017-03-31","subitem_date_issued_type":"Issued"}]},"item_10007_description_13":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"研究成果の概要(和文):終夜睡眠ポリソムノグラフィ検査でSASと診断された患者39名(男性25名、女性14名)を対象とし、血液検査結果の解析を行った。靭帯石灰化に関する過去の報告と同様、無機質代謝やアルカリフォスファターゼには、顕著な異常は認められなかった。靭帯骨化症に関連するとされるレプチン濃度は、男性で2.0~26.8ng/ml、女性で3.8~34.8ng/mlに分布し、39名中9名(男性5名、女性4名)が異常な高値(男性13.0 ng/ml以上、女性21.8 ng/ml以上)を示した。レプチン濃度は、肥満度(BMI)と正の相関が認められ、加えて、SAS重症度(AHI)との間にも正の相関が認められた。","subitem_description_language":"ja","subitem_description_type":"Abstract"},{"subitem_description":"研究成果の概要(英文):Last year we investigated the characteristics of sleep apnea in patients from the results of their blood tests. The blood tests were performed on 39 patients (Male:25, Female:14) with sleep apnea syndrome (SAS) who were diagnosed using full-night polysomnography. There were no morbid findings in mineral metabolism or levels of Alkaline phosphatase. These results correspond to previous studies regarding the calcification of ligaments. In a previous study, it had been reported that Leptin may be related with ligament osteosis. The level of Leptin in the male SAS patients ranged from 2.0 to 26.8 ng/ml, and from 3.8 to 34.8 ng/ml in the female SAS patients. In nine (Male:5, Female:4) of the 39 patients, the level of Leptin indicated an abnormal value, over 13.0 ng/ml in the males, and over 21.8 ng/ml in the females. In addition, there were significant positive correlations between the level of Leptin and obesity (Body mass index: BMI), and SAS severity (Apnea-hypoapnea index: AHI).","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10007_description_14":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"・2016(平成28)年度 科学研究費補助金 基盤研究(C) 研究成果報告書","subitem_description_language":"ja","subitem_description_type":"Other"},{"subitem_description":"・研究期間 (年度):2014-04-01 – 2017-03-31","subitem_description_language":"ja","subitem_description_type":"Other"},{"subitem_description":"・研究分野:睡眠時無呼吸症候群","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_10007_description_9":{"attribute_name":"研究課題番号","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号 : 26461093","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_10007_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-26461093/","subitem_relation_type_select":"URI"}}]},"item_10007_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-04-19"}],"displaytype":"detail","filename":"26461093.pdf","filesize":[{"value":"465.8 kB"}],"format":"application/pdf","licensetype":"license_6","mimetype":"application/pdf","url":{"label":"26461093","url":"https://tsurumi-u.repo.nii.ac.jp/record/1140/files/26461093.pdf"},"version_id":"960e1ec3-68bb-4afa-b900-4a3850ddbf89"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"睡眠時無呼吸症候群","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"靭帯石灰化","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"レプチン","subitem_subject_language":"ja","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_researcher":{"attribute_name":"研究代表者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"安藤, 栄里子","creatorNameLang":"ja"},{"creatorName":"ANDO, Eriko","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{}]}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"睡眠時無呼吸症候群と頸部石灰化物の関連性の検討","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"睡眠時無呼吸症候群と頸部石灰化物の関連性の検討","subitem_title_language":"ja"},{"subitem_title":"Assessment of the Calcification of the Nuchal Ligament and Osteophytes of the Cervical Spine in Obstructive Sleep Apnea Subjects and Snorers.","subitem_title_language":"en"}]},"item_type_id":"10007","owner":"10","path":["177"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2022-04-19"},"publish_date":"2022-04-19","publish_status":"0","recid":"1140","relation_version_is_last":true,"title":["睡眠時無呼吸症候群と頸部石灰化物の関連性の検討"],"weko_creator_id":"10","weko_shared_id":-1},"updated":"2024-01-15T02:32:21.066897+00:00"}