@techreport{oai:tsurumi-u.repo.nii.ac.jp:00001140, author = {安藤, 栄里子 and ANDO, Eriko}, month = {Mar}, note = {研究成果の概要(和文):終夜睡眠ポリソムノグラフィ検査でSASと診断された患者39名(男性25名、女性14名)を対象とし、血液検査結果の解析を行った。靭帯石灰化に関する過去の報告と同様、無機質代謝やアルカリフォスファターゼには、顕著な異常は認められなかった。靭帯骨化症に関連するとされるレプチン濃度は、男性で2.0~26.8ng/ml、女性で3.8~34.8ng/mlに分布し、39名中9名(男性5名、女性4名)が異常な高値(男性13.0 ng/ml以上、女性21.8 ng/ml以上)を示した。レプチン濃度は、肥満度(BMI)と正の相関が認められ、加えて、SAS重症度(AHI)との間にも正の相関が認められた。, 研究成果の概要(英文):Last year we investigated the characteristics of sleep apnea in patients from the results of their blood tests. The blood tests were performed on 39 patients (Male:25, Female:14) with sleep apnea syndrome (SAS) who were diagnosed using full-night polysomnography. There were no morbid findings in mineral metabolism or levels of Alkaline phosphatase. These results correspond to previous studies regarding the calcification of ligaments. In a previous study, it had been reported that Leptin may be related with ligament osteosis. The level of Leptin in the male SAS patients ranged from 2.0 to 26.8 ng/ml, and from 3.8 to 34.8 ng/ml in the female SAS patients. In nine (Male:5, Female:4) of the 39 patients, the level of Leptin indicated an abnormal value, over 13.0 ng/ml in the males, and over 21.8 ng/ml in the females. In addition, there were significant positive correlations between the level of Leptin and obesity (Body mass index: BMI), and SAS severity (Apnea-hypoapnea index: AHI)., ・2016(平成28)年度 科学研究費補助金 基盤研究(C) 研究成果報告書, ・研究期間 (年度):2014-04-01 – 2017-03-31, ・研究分野:睡眠時無呼吸症候群, 研究課題/領域番号 : 26461093}, title = {睡眠時無呼吸症候群と頸部石灰化物の関連性の検討}, year = {2017} }