{"created":"2023-05-15T08:55:49.746688+00:00","id":1057,"links":{},"metadata":{"_buckets":{"deposit":"6f2690e6-29c0-4f54-8076-8ec81fd1e910"},"_deposit":{"created_by":10,"id":"1057","owners":[10],"pid":{"revision_id":0,"type":"depid","value":"1057"},"status":"published"},"_oai":{"id":"oai:tsurumi-u.repo.nii.ac.jp:00001057","sets":["100:101:103:160"]},"author_link":["803"],"item_10007_date_8":{"attribute_name":"報告年度","attribute_value_mlt":[{"subitem_date_issued_datetime":"2019-03-31","subitem_date_issued_type":"Issued"}]},"item_10007_description_13":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"研究成果の概要（和文）：義歯床プラークの除去方法を開発するための基礎研究として、菌叢特性と付着メカニズムの解析を行った。義歯床プラーク細菌の菌叢解析として、T-RFLP法を行ったところ金属間で付着する菌叢が異なる可能性が示唆され、次世代シーケンサーによる遺伝子配列決定法を用いた結果、菌属レベルが異なっていることが確認された。その要因は菌の付着レセプターとなるペリクル様タンパク質も異なる可能性が考えられたので、純チタンとCo-Cr、義歯床用レジンを用いて付着唾液タンパク質の比較を行った。その結果、共通なものと特有なものとが検出された。このことから材料ごとに付着する唾液タンパク質が選択されていることが示唆された。","subitem_description_language":"ja","subitem_description_type":"Abstract"},{"subitem_description":"研究成果の概要（英文）：As a basic research to develop a method for removing denture base plaques, we analyzed microflora characteristics and adhesion mechanism. From the result of a comprehensive bacterial flora analysis of denture base plaque bacteria, T-RFLP method suggested that the flora attached might be different among metals. Then using gene sequencing method with next generation sequencer, it was confirmed that the genus level was different. It is thought that the factors may differ from pellicle-like proteins, which are receptors to which bacteria attach, so we compared salivary proteins attached using pure titanium, Co-Cr, and denture base resin. As a result, common and unique proteins were detected. This suggests that saliva proteins adhering to each material are selected.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10007_description_14":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"・2018(平成30)年度 科学研究費補助金 若手研究(B) 研究成果報告書","subitem_description_language":"ja","subitem_description_type":"Other"},{"subitem_description":"・研究期間 (年度)：2016-04-01 – 2019-03-31","subitem_description_language":"ja","subitem_description_type":"Other"},{"subitem_description":"・研究分野：有床義歯補綴学","subitem_description_language":"ja","subitem_description_type":"Other"},{"subitem_description":"・研究成果の学術的意義や社会的意義 : 可綴性義歯の使用はプラークの付着が避けられず、義歯使用率の高い高齢者には誤嚥性肺炎などを避けるためにもデンチャープラークコントロールが非常に重要である。現在、義歯の清掃は化学的洗浄と機械的洗浄に依存しているが、義歯に対するプラークの付着自体を抑制することで義歯管理は飛躍的に簡便となり、要介護者を含め全身疾患への予防につながる。本研究は、各材料における付着メカニズムおよび菌叢特性の一端を見つけることができたので、デンチャープラークの付着防止および除去法を開発するための基礎的情報として有用であると思われた。","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_10007_description_9":{"attribute_name":"研究課題番号","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号 : 16K20522","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_10007_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-16K20522/","subitem_relation_type_select":"URI"}}]},"item_10007_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-03-16"}],"displaytype":"detail","filename":"16K20522.pdf","filesize":[{"value":"572.1 kB"}],"format":"application/pdf","licensetype":"license_6","mimetype":"application/pdf","url":{"label":"16K20522","url":"https://tsurumi-u.repo.nii.ac.jp/record/1057/files/16K20522.pdf"},"version_id":"fa729233-bc0f-47e5-a18d-03b8c2d50cff"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"有床義歯補綴学","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"義歯ケア","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"菌叢","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"デンチャープラーク","subitem_subject_language":"ja","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_researcher":{"attribute_name":"研究代表者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"URUSHIBARA, Yu","creatorNameLang":"en"},{"creatorName":"漆原, 優","creatorNameLang":"ja"},{"creatorName":"ウルシバラ, ユウ","creatorNameLang":"ja-Kana"}],"familyNames":[{"familyName":"URUSHIBARA","familyNameLang":"en"},{"familyName":"漆原","familyNameLang":"ja"},{"familyName":"ウルシバラ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Yu","givenNameLang":"en"},{"givenName":"優","givenNameLang":"ja"},{"givenName":"ユウ","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"803","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"90735680","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=90735680"},{"nameIdentifier":"803","nameIdentifierScheme":"WEKO著者ID"}]}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"義歯床プラークの菌叢特性と付着メカニズムの解析と除去方法の開発","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"義歯床プラークの菌叢特性と付着メカニズムの解析と除去方法の開発","subitem_title_language":"ja"},{"subitem_title":"Analysis of microflora characteristics in denture base plaque and adhesion mechanism for development of removal method.","subitem_title_language":"en"}]},"item_type_id":"10007","owner":"10","path":["160"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2022-03-16"},"publish_date":"2022-03-16","publish_status":"0","recid":"1057","relation_version_is_last":true,"title":["義歯床プラークの菌叢特性と付着メカニズムの解析と除去方法の開発"],"weko_creator_id":"10","weko_shared_id":-1},"updated":"2024-08-01T23:42:37.515357+00:00"}