{"created":"2023-05-15T08:55:49.490945+00:00","id":1053,"links":{},"metadata":{"_buckets":{"deposit":"3f9fcb06-a524-4975-a8f3-c5a5f50061ee"},"_deposit":{"created_by":10,"id":"1053","owners":[10],"pid":{"revision_id":0,"type":"depid","value":"1053"},"status":"published"},"_oai":{"id":"oai:tsurumi-u.repo.nii.ac.jp:00001053","sets":["100:101:103:160"]},"author_link":["799"],"item_10007_date_8":{"attribute_name":"報告年度","attribute_value_mlt":[{"subitem_date_issued_datetime":"2019-03-31","subitem_date_issued_type":"Issued"}]},"item_10007_description_13":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"研究成果の概要（和文）：本研究は、次世代シークエンサーを用いて炎症性腸疾患（Inflammatory Bowel Disease: IBD）患者と健康ボランティアの口腔内細菌叢と腸内細菌叢の均衡と多様性について検証を行った。その結果、IBD患者と健康ボランティアともに腸内細菌サンプル中に口腔細菌が存在することがわかった。さらにIBD患者および健康ボランティアの腸内における口腔細菌の細菌構造は異なることも明らかになった。","subitem_description_language":"ja","subitem_description_type":"Abstract"},{"subitem_description":"研究成果の概要（英文）：Oral and fecal microbiota from volunteers having inflammatory bowel disease (IBD) were investigated using an advanced next generation sequencing technology and compared with those of healthy volunteers. Oral and fecal samples of ten healthy volunteers and 12 IBD volunteers were sequenced after extracting whole DNA using a 16S rRNA sequencing on the Ion Torrent Personal Genome Machine (I-PGM) System. Streptococcus salivarius and Streptococcus oralis were detected in both oral and fecal samples collected from most volunteers in either group. Streptococcus mutans, Streptococcus gordonii and Actinomyces spp. were present in both samples of few volunteers. Granulicatella adiacens and Streptococcus salivarius were detected in both oral and fecal samples collected from three IBD volunteers. All volunteers from both groups had Streptococcus sinensis in their oral cavity. With few exceptions most volunteers had Streptococcus sinensis in their fecal samples.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10007_description_14":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"・2018(平成30)年度 科学研究費補助金 研究活動スタート支援 研究成果報告書","subitem_description_language":"ja","subitem_description_type":"Other"},{"subitem_description":"・研究期間 (年度)：2017-08-25 – 2019-03-31","subitem_description_language":"ja","subitem_description_type":"Other"},{"subitem_description":"・研究分野：社会歯学","subitem_description_language":"ja","subitem_description_type":"Other"},{"subitem_description":"・研究成果の学術的意義や社会的意義 : 近年、IBDの患者数は急増しているにも関わらず、根本原因がわからないため、効果的な予防方法や根治療法は確立していない。本研究によりIBD患者の口腔および腸内細菌叢から細菌学的な知見が得られたことにより、予防方法や根治療法の発見の一助となることが期待される。","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_10007_description_9":{"attribute_name":"研究課題番号","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号 : 17H07200","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_10007_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-17H07200/","subitem_relation_type_select":"URI"}}]},"item_10007_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-03-16"}],"displaytype":"detail","filename":"17H07200.pdf","filesize":[{"value":"148.1 kB"}],"format":"application/pdf","licensetype":"license_6","mimetype":"application/pdf","url":{"label":"17H07200","url":"https://tsurumi-u.repo.nii.ac.jp/record/1053/files/17H07200.pdf"},"version_id":"d289ecea-2916-48c4-a178-69d37f043953"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"口腔細菌叢","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"腸内細菌叢","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"炎症性腸疾患","subitem_subject_language":"ja","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_researcher":{"attribute_name":"研究代表者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"OTSUKA, Ryoko","creatorNameLang":"en"},{"creatorName":"大塚, 良子","creatorNameLang":"ja"},{"creatorName":"オオツカ, リョウコ","creatorNameLang":"ja-Kana"}],"familyNames":[{"familyName":"OTSUKA","familyNameLang":"en"},{"familyName":"大塚","familyNameLang":"ja"},{"familyName":"オオツカ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Ryoko","givenNameLang":"en"},{"givenName":"良子","givenNameLang":"ja"},{"givenName":"リョウコ","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"799","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"00803701","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=00803701"},{"nameIdentifier":"799","nameIdentifierScheme":"WEKO著者ID"}]}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"炎症性腸疾患患者の口腔・腸内細菌叢の均衡と多様性についての基礎的研究","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"炎症性腸疾患患者の口腔・腸内細菌叢の均衡と多様性についての基礎的研究","subitem_title_language":"ja"},{"subitem_title":"Metagenomics on Oral Bacteria and Fecal Bacteria using a Next Generation Sequencing System","subitem_title_language":"en"}]},"item_type_id":"10007","owner":"10","path":["160"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2022-03-16"},"publish_date":"2022-03-16","publish_status":"0","recid":"1053","relation_version_is_last":true,"title":["炎症性腸疾患患者の口腔・腸内細菌叢の均衡と多様性についての基礎的研究"],"weko_creator_id":"10","weko_shared_id":-1},"updated":"2024-08-01T23:28:21.204774+00:00"}