{"created":"2023-05-15T08:55:47.491175+00:00","id":1016,"links":{},"metadata":{"_buckets":{"deposit":"69be859d-d0cf-4e5d-b25a-c18ea508e8e2"},"_deposit":{"created_by":10,"id":"1016","owners":[10],"pid":{"revision_id":0,"type":"depid","value":"1016"},"status":"published"},"_oai":{"id":"oai:tsurumi-u.repo.nii.ac.jp:00001016","sets":["100:101:103:157"]},"author_link":["773"],"item_10007_date_8":{"attribute_name":"報告年度","attribute_value_mlt":[{"subitem_date_issued_datetime":"2020-03-31","subitem_date_issued_type":"Issued"}]},"item_10007_description_13":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"研究成果の概要（和文）：歯科治療において，チタン（Ti）インプラントは顎骨と結合することによって機能している．顎骨と結合するためには，まずTiへのタンパク質の吸着が重要である．本研究では，微量なタンパク質の吸着挙動をその場で観察できる水晶発振子マイクロバランス（QCM）法を用いてタンパク質のTiに対する吸着を検討した．その結果，カルシウムイオンによる修飾がTiに対するタンパク質の吸着を高めること，および異なったタンパク質の2段階吸着において吸着順序によってTiへの吸着挙動が異なることが判明した．","subitem_description_language":"ja","subitem_description_type":"Abstract"},{"subitem_description":"研究成果の概要（英文）：Titanium（Ti）implants function by bonding to jawbone. For getting the bonding to jawbone, the adsorption of proteins onto Ti is important. In the present study, we investigated the adsorption of proteins to Ti by using quartz crystal microbalance（QCM）method which can detect the adsorption of small amounts of proteins in situ. As results, it revealed that the modification of Ca ion enhanced the adsorption of proteins onto Ti and that adsorption orders of the proteins influence the adsorption behaviors in the case of two-step adsorption for different proteins..","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10007_description_14":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"・2019(令和元)年度 科学研究費補助金 基盤研究(C) 研究成果報告書","subitem_description_language":"ja","subitem_description_type":"Other"},{"subitem_description":"・研究期間 (年度)：2017-04-01 – 2020-03-31","subitem_description_language":"ja","subitem_description_type":"Other"},{"subitem_description":"・研究分野：歯科理工学","subitem_description_language":"ja","subitem_description_type":"Other"},{"subitem_description":"・研究成果の学術的意義や社会的意義 : Tiインプラントの顎骨との結合，いわゆるオッセオインテグレーション獲得のメカニズムを理解するために，生体内を模倣した状態でのタンパク質の吸着という観点から検討を試みた．その結果，タンパク質吸着に関する新たな知見が得られ，オッセオインテグレーション獲得のメカニズムに関して貴重な示唆を得ることができた．さらに，歯科用Tiインプラント表面の特性についてより詳細に明らかにすることができ，新たな歯科用Tiインプラント表面の創製に繋がることが期待できる．","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_10007_description_9":{"attribute_name":"研究課題番号","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号 : 17K11815","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_10007_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-17K11815/","subitem_relation_type_select":"URI"}}]},"item_10007_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-03-08"}],"displaytype":"detail","filename":"17K11815.pdf","filesize":[{"value":"864.9 kB"}],"format":"application/pdf","licensetype":"license_6","mimetype":"application/pdf","url":{"label":"17K11815","url":"https://tsurumi-u.repo.nii.ac.jp/record/1016/files/17K11815.pdf"},"version_id":"d4b4a78c-a7c1-4f12-a57b-6d5b61a4eefa"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"チタンインプラント","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"オッセオインテグレーション","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"水晶発振子マイクロバランス","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"タンパク質吸着","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"フィブロネクチン","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"アルブミン","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"カルシウムイオン","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"2段階吸着","subitem_subject_language":"ja","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_researcher":{"attribute_name":"研究代表者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"HAYAKAWA, Tohru","creatorNameLang":"en"},{"creatorName":"早川, 徹","creatorNameLang":"ja"},{"creatorName":"ハヤカワ, トオル","creatorNameLang":"ja-Kana"}],"familyNames":[{"familyName":"HAYAKAWA","familyNameLang":"en"},{"familyName":"早川","familyNameLang":"ja"},{"familyName":"ハヤカワ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Tohru","givenNameLang":"en"},{"givenName":"徹","givenNameLang":"ja"},{"givenName":"トオル","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"773","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"40172994","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=40172994"},{"nameIdentifier":"773","nameIdentifierScheme":"WEKO著者ID"}]}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"オッセオインテグレーション理解のためのQCM法による基礎的アプローチ","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"オッセオインテグレーション理解のためのQCM法による基礎的アプローチ","subitem_title_language":"ja"},{"subitem_title":"Basic approach for understanding the osseointegration by QCM method","subitem_title_language":"en"}]},"item_type_id":"10007","owner":"10","path":["157"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2022-03-08"},"publish_date":"2022-03-08","publish_status":"0","recid":"1016","relation_version_is_last":true,"title":["オッセオインテグレーション理解のためのQCM法による基礎的アプローチ"],"weko_creator_id":"10","weko_shared_id":-1},"updated":"2024-08-01T08:43:14.263524+00:00"}